Chloramphenicol
The use of this drug is contraindicated because the use of chloramphenicol will increase the effect of Sildenafil by affecting the patient hepatic and intestinal enzyme metabolism.
Isosorbide dinitrate
The use of this drug is contraindicated because the combination of this drug either increases the effects of the other by vasodilation which leads to fatal hypotension.
Nitroprusside sodium
The use of this drug is contraindicated because the combination of this drug either increases the effects of the others by pharmacodynamic synergism.
Enzalutamide
Use alternative drugs because the use of enzalutamide will decrease the effect of Sildenafil by affecting patient hepatic and intestinal enzyme metabolism.
Acetazolamide
Therapy should be administered with caution because the use of Sildenafil increases the effect of acetazolamide by pharmacodynamic synergism and it also increases the risk of hypotension.
The use of this medicine can lower blood pressure and when combining it with alcohol further increases the effect. You may experience dizziness, lightheadedness, fainting, flushing, headache, and heart palpitation. Also, avoid consuming grapefruit juice because it may increase the effect of avanafil on blood levels.
Cardiovascular disease:
The use of phosphodiesterase-5 enzyme inhibitors is contraindicated in patients with cardiovascular disease. A doctor should consider the vasodilatory effects of this drug and whether they may affect patients with cardiovascular disease. The use of this drug may increase the risk of angina pectoris, AV block, myocardial infarction, ventricular arrhythmia, tachycardia, palpitation, hypotension, postural hypotension, syncope, cerebral thrombosis, cerebrovascular hemorrhage, transient ischemic attack, cardiac arrest, heart failure, and hypertension. These events can occur during or after sexual activity.
Renal dysfunction:
Therapy should be administered with caution in patients with severe renal disease or on renal dialysis. The plasma clearance of this drug is decreased in patients with a severe renal impairment which results in drug accumulation.
Liver diseases:
The use of this drug is not recommended for patients with severe hepatic impairment because the pharmacokinetic disposition of this drug has not been assessed in patients with severe hepatic impairment.
AddendumA drug ismissARMs when it is not received in the prior few hundredilling year.
The use of this drug is not recommended for patients with food intolerances because the use of this drug may increase the effect of Sildenafil by affecting patient hepatic and intestinal enzyme metabolism.
is an inhibitor of phosphodiesterase-5 enzyme. When this enzyme is inhibited the blood vessels dilate and the drug attaches to the inhibitory group of the enzyme and causes an increase in the plasma concentration of the drug in the body. This leads to an accumulation of the drug in the patient.
Cerebral Palsy
Therapy should be administered with caution in patients with cerebral palsy due to the possible risk of orthostatic hypotension.
The use of phosphodiesterase-5 enzyme inhibitors is not recommended in patients with nutritional Interaction because the pharmacokinetic disposition of this drug has not been assessed in patients with nutritional Interaction. The use of this drug may increase the effect of Sildenafil by phyticInteraction with Grapefruit Juice.
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Product details
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